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P32067

Lupus La protein homolog (P32067)

Uniprot ID P32067
Protein Name Lupus La protein homolog
Gene Name Ssb
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.563
Function Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
GO - Molecular function
  • poly(U) RNA binding : ISO:MGI
  • RNA binding : IDA:MGI
  • sequence-specific mRNA binding : ISO:MGI
  • tRNA binding : ISO:MGI
GO - Biological process
  • IRES-dependent viral translational initiation : ISO:MGI
  • nuclear histone mRNA catabolic process : ISO:MGI
  • protein localization to cytoplasmic stress granule : ISO:MGI
  • tRNA 3'-end processing : ISO:MGI
  • tRNA 5'-leader removal : ISO:MGI
  • tRNA export from nucleus : ISO:MGI
  • tRNA processing : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.