Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
P31786

Acyl-CoA-binding protein (P31786)

Uniprot ID P31786
Protein Name Acyl-CoA-binding protein
Gene Name Dbi
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.87
Function Binds medium-and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
GO - Molecular function
  • benzodiazepine receptor binding : ISO:MGI
  • fatty-acyl-CoA binding : ISO:MGI
  • lipid binding : IEA:UniProtKB-KW
  • long-chain fatty acyl-CoA binding : ISO:MGI
  • protein dimerization activity : ISO:MGI
GO - Biological process
  • behavioral fear response : IDA:MGI
  • glial cell proliferation : ISO:MGI
  • hair follicle development : IMP:MGI
  • lateral ventricle development : IDA:MGI
  • learning or memory : IDA:MGI
  • long-term synaptic potentiation : IDA:MGI
  • negative regulation of fatty acid beta-oxidation : ISO:MGI
  • phosphatidylcholine acyl-chain remodeling : ISO:MGI
  • positive regulation of lipid biosynthetic process : ISO:MGI
  • positive regulation of release of sequestered calcium ion into cytosol : ISO:MGI
  • regulation of synaptic transmission, GABAergic : ISO:MGI
  • skin development : IMP:MGI
  • triglyceride metabolic process : IMP:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.