Signal peptide(a) |
N |
Secretome P(b) |
0.872 |
Function |
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. . |
GO - Molecular function |
- antioxidant activity : IDA:UniProtKB
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process : IMP:UniProtKB
- peroxidase activity : IDA:UniProtKB
- peroxiredoxin activity : IDA:UniProtKB
- peroxynitrite reductase activity : IDA:UniProtKB
- RNA polymerase III regulatory region DNA binding : IDA:UniProtKB
- signaling receptor binding : IPI:UniProtKB
- thioredoxin peroxidase activity : EXP:Reactome
|
GO - Biological process |
- cell redox homeostasis : IBA:GO_Central
- cellular response to oxidative stress : IBA:GO_Central
- cellular response to reactive oxygen species : IMP:UniProtKB
- hydrogen peroxide catabolic process : IDA:UniProtKB
- inflammatory response : TAS:UniProtKB
- NADPH oxidation : IDA:UniProtKB
- negative regulation of apoptotic process : IMP:UniProtKB
- negative regulation of oxidoreductase activity : IDA:UniProtKB
- negative regulation of transcription by RNA polymerase III : IDA:UniProtKB
- positive regulation of collagen biosynthetic process : IDA:UniProtKB
- reactive nitrogen species metabolic process : IDA:UniProtKB
- regulation of apoptosis involved in tissue homeostasis : IDA:UniProtKB
- response to oxidative stress : IDA:UniProtKB
|