| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. |
| GO - Molecular function |
- ammonium transmembrane transporter activity : ISS:UniProtKB
- carbon dioxide transmembrane transporter activity : ISS:UniProtKB
- ephrin receptor binding : ISO:RGD
- glycerol transmembrane transporter activity : IDA:UniProtKB
- identical protein binding : ISO:RGD
- intracellular cGMP-activated cation channel activity : ISS:UniProtKB
- nitric oxide transmembrane transporter activity : ISS:UniProtKB
- potassium channel activity : ISS:UniProtKB
- potassium ion transmembrane transporter activity : ISO:RGD
- transmembrane transporter activity : ISO:RGD
- water channel activity : IMP:RGD
- water transmembrane transporter activity : ISO:RGD
|
| GO - Biological process |
- ammonium transport : ISS:UniProtKB
- camera-type eye morphogenesis : ISO:RGD
- carbon dioxide transmembrane transport : ISS:UniProtKB
- carbon dioxide transport : ISS:UniProtKB
- cell volume homeostasis : ISS:UniProtKB
- cellular homeostasis : ISS:UniProtKB
- cellular hyperosmotic response : ISS:UniProtKB
- cellular response to cAMP : ISS:UniProtKB
- cellular response to copper ion : ISS:UniProtKB
- cellular response to dexamethasone stimulus : ISS:UniProtKB
- cellular response to hydrogen peroxide : ISS:UniProtKB
- cellular response to hypoxia : ISS:UniProtKB
- cellular response to inorganic substance : ISS:UniProtKB
- cellular response to mechanical stimulus : ISS:UniProtKB
- cellular response to mercury ion : ISS:UniProtKB
- cellular response to nitric oxide : ISO:RGD
- cellular response to retinoic acid : ISS:UniProtKB
- cellular response to salt stress : ISS:UniProtKB
- cellular response to UV : ISS:UniProtKB
- cellular water homeostasis : ISS:UniProtKB
- cerebrospinal fluid secretion : ISO:RGD
- cGMP-mediated signaling : ISS:UniProtKB
- corticotropin secretion : ISO:RGD
- establishment or maintenance of actin cytoskeleton polarity : ISS:UniProtKB
- glomerular filtration : ISO:RGD
- glycerol transport : IDA:UniProtKB
- hyperosmotic response : IEP:RGD
- hyperosmotic salinity response : IEP:RGD
- lateral ventricle development : IEP:UniProtKB
- lipid digestion : ISO:RGD
- maintenance of symbiont-containing vacuole by host : ISS:UniProtKB
- metanephric descending thin limb development : ISO:RGD
- metanephric glomerulus vasculature development : ISO:RGD
- metanephric proximal convoluted tubule segment 2 development : ISO:RGD
- metanephric proximal straight tubule development : ISO:RGD
- multicellular organismal water homeostasis : ISO:RGD
- negative regulation of apoptotic process : ISS:UniProtKB
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process : ISO:RGD
- nitric oxide transport : ISS:UniProtKB
- odontogenesis : ISO:RGD
- pancreatic juice secretion : ISO:RGD
- positive regulation of angiogenesis : ISS:UniProtKB
- positive regulation of cell migration : ISO:RGD
- positive regulation of epithelial cell migration : IMP:RGD
- positive regulation of fibroblast proliferation : ISS:UniProtKB
- positive regulation of lamellipodium assembly : IMP:RGD
- positive regulation of saliva secretion : ISS:UniProtKB
- potassium ion transport : ISO:RGD
- renal water absorption : ISO:RGD
- renal water transport : ISS:UniProtKB
- response to drug : ISS:UniProtKB
- response to estrogen : IEP:RGD
- response to hormone : IEP:RGD
- secretion by cell : ISO:RGD
- secretory granule organization : ISO:RGD
- sensory perception of pain : ISO:RGD
- transepithelial water transport : ISS:UniProtKB
- water homeostasis : ISO:RGD
- water transport : IMP:RGD
- wound healing : ISO:RGD
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