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P29416

Beta-hexosaminidase subunit alpha (P29416)

Uniprot ID P29416
Protein Name Beta-hexosaminidase subunit alpha
Gene Name Hexa
Species Mus musculus (Mouse)
Basic Information Experiments (5) Disease (5) Interactions
Signal peptide(a) Y Secretome P(b) 0.709
Function Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
GO - Molecular function
  • acetylglucosaminyltransferase activity : ISO:MGI
  • beta-N-acetylhexosaminidase activity : IDA:MGI
  • N-acetyl-beta-D-galactosaminidase activity : IEA:UniProtKB-EC
  • protein heterodimerization activity : ISO:MGI
GO - Biological process
  • adult walking behavior : IMP:MGI
  • carbohydrate metabolic process : IEA:InterPro
  • cell morphogenesis involved in neuron differentiation : IMP:MGI
  • ganglioside catabolic process : IMP:MGI
  • glycosaminoglycan biosynthetic process : ISO:MGI
  • glycosaminoglycan metabolic process : IGI:MGI
  • lipid storage : IMP:MGI
  • locomotory behavior : IGI:MGI
  • lysosome organization : IMP:MGI
  • myelination : IGI:MGI
  • neuromuscular process controlling balance : IGI:MGI
  • neuromuscular process controlling posture : IMP:MGI
  • sensory perception of sound : IGI:MGI
  • sexual reproduction : IMP:MGI
  • skeletal system development : IGI:MGI
  • SMAD protein signal transduction : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.