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P29400

Collagen alpha-5(IV) chain (P29400)

Uniprot ID P29400
Protein Name Collagen alpha-5(IV) chain
Gene Name COL4A5
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.141
Function Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
GO - Molecular function
  • extracellular matrix structural constituent : IEA:InterPro
GO - Biological process
  • collagen-activated tyrosine kinase receptor signaling pathway : IEA:Ensembl
  • extracellular matrix organization : TAS:Reactome
  • neuromuscular junction development : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.