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P24043

Laminin subunit alpha-2 (P24043)

Uniprot ID P24043
Protein Name Laminin subunit alpha-2
Gene Name LAMA2
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.393
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
GO - Molecular function
  • signaling receptor binding : IEA:InterPro
  • structural molecule activity : TAS:ProtInc
GO - Biological process
  • axon guidance : IEA:Ensembl
  • cell adhesion : IEA:UniProtKB-KW
  • extracellular matrix organization : TAS:Reactome
  • muscle organ development : TAS:ProtInc
  • positive regulation of synaptic transmission, cholinergic : IEA:Ensembl
  • regulation of cell adhesion : IEA:InterPro
  • regulation of cell migration : IEA:InterPro
  • regulation of embryonic development : IEA:InterPro
  • Schwann cell differentiation : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.