Signal peptide(a) |
Y |
Secretome P(b) |
0.217 |
Function |
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. . |
GO - Molecular function |
- endopeptidase activity : ISO:MGI
- metal ion binding : IEA:UniProtKB-KW
- nerve growth factor binding : ISO:MGI
- peptidase activity : ISO:MGI
- peptide binding : ISO:MGI
- protease binding : ISO:MGI
- serine-type endopeptidase activity : EXP:Reactome
- serine-type endopeptidase inhibitor activity : ISO:MGI
|
GO - Biological process |
- cell proliferation : ISO:MGI
- dibasic protein processing : ISO:MGI
- negative regulation of low-density lipoprotein particle receptor catabolic process : ISO:MGI
- negative regulation of transforming growth factor beta1 production : ISO:MGI
- nerve growth factor production : ISO:MGI
- peptide biosynthetic process : ISO:MGI
- peptide hormone processing : ISO:MGI
- positive regulation of cell migration : ISO:MGI
- positive regulation of transforming growth factor beta receptor signaling pathway : ISO:MGI
- protein processing : IDA:MGI
- regulation of endopeptidase activity : ISO:MGI
- regulation of low-density lipoprotein particle receptor biosynthetic process : IMP:MGI
- regulation of protein catabolic process : ISO:MGI
- regulation of signal transduction : IDA:MGI
- secretion by cell : ISO:MGI
- signal peptide processing : ISO:MGI
- viral life cycle : IEA:Ensembl
- zymogen activation : ISO:MGI
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