Biglycan (P21810)

Uniprot ID P21810
Protein Name Biglycan
Gene Name BGN
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.657
Function May be involved in collagen fiber assembly. .
GO - Molecular function
  • extracellular matrix binding : IEA:Ensembl
  • extracellular matrix structural constituent : NAS:UniProtKB
  • extracellular matrix structural constituent conferring compression resistance : ISS:BHF-UCL
  • glycosaminoglycan binding : IEA:Ensembl
GO - Biological process
  • articular cartilage development : IEA:Ensembl
  • blood vessel remodeling : IEA:Ensembl
  • bone development : IEA:Ensembl
  • chondroitin sulfate biosynthetic process : TAS:Reactome
  • chondroitin sulfate catabolic process : TAS:Reactome
  • dermatan sulfate biosynthetic process : TAS:Reactome
  • extracellular matrix organization : TAS:Reactome
  • peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.