Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
P21589

5'-nucleotidase (P21589)

Uniprot ID P21589
Protein Name 5'-nucleotidase
Gene Name NT5E
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.65
Function Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. .
GO - Molecular function
  • 5'-nucleotidase activity : IDA:CACAO
  • metal ion binding : IEA:UniProtKB-KW
  • nucleotide binding : IEA:UniProtKB-KW
GO - Biological process
  • adenosine biosynthetic process : IEA:Ensembl
  • AMP catabolic process : IEA:Ensembl
  • DNA metabolic process : TAS:ProtInc
  • leukocyte cell-cell adhesion : IDA:CACAO
  • NAD metabolic process : TAS:Reactome
  • negative regulation of inflammatory response : IEA:Ensembl
  • purine nucleotide catabolic process : TAS:Reactome
  • pyrimidine nucleoside catabolic process : TAS:Reactome
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.