Peptidyl-prolyl cis-trans isomerase A (P17742)

Uniprot ID P17742
Protein Name Peptidyl-prolyl cis-trans isomerase A
Gene Name Ppia
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.729
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
GO - Molecular function
  • cyclosporin A binding : ISS:UniProtKB
  • peptidyl-prolyl cis-trans isomerase activity : ISS:UniProtKB
GO - Biological process
  • lipid particle organization : ISO:MGI
  • neuron differentiation : IMP:MGI
  • positive regulation of protein secretion : ISO:MGI
  • positive regulation of viral genome replication : ISO:MGI
  • protein folding : IEA:InterPro
  • protein peptidyl-prolyl isomerization : ISS:UniProtKB
  • regulation of viral genome replication : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.