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P16546

Spectrin alpha chain, non-erythrocytic 1 (P16546)

Uniprot ID P16546
Protein Name Spectrin alpha chain, non-erythrocytic 1
Gene Name Sptan1
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.324
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • cadherin binding : ISO:MGI
  • calcium ion binding : IEA:InterPro
  • calmodulin binding : IEA:UniProtKB-KW
  • protein heterodimerization activity : IDA:MGI
  • protein N-terminus binding : ISO:MGI
  • protein-containing complex binding : ISO:MGI
  • spectrin binding : IDA:MGI
  • syntaxin binding : ISO:MGI
GO - Biological process
  • actin cytoskeleton reorganization : ISO:MGI
  • actin filament capping : IEA:UniProtKB-KW
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.