Neural cell adhesion molecule 1 (P13596)

Uniprot ID P13596
Protein Name Neural cell adhesion molecule 1
Gene Name Ncam1
Species Rattus norvegicus (Rat)
Signal peptide(a) Y Secretome P(b) 0.0
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
GO - Molecular function
  • cytoskeletal protein binding : TAS:RGD
  • fibroblast growth factor receptor binding : TAS:RGD
  • heparin binding : IEA:UniProtKB-KW
  • identical protein binding : ISO:RGD
  • LRR domain binding : IPI:RGD
  • phosphatase binding : IDA:RGD
GO - Biological process
  • aging : IDA:RGD
  • animal organ regeneration : IEP:RGD
  • axonal fasciculation : IMP:RGD
  • calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules : TAS:RGD
  • cell adhesion : TAS:RGD
  • cell surface receptor signaling pathway : ISO:RGD
  • cellular response to inorganic substance : IEP:RGD
  • cellular response to molecule of bacterial origin : IEP:RGD
  • commissural neuron axon guidance : ISO:RGD
  • homotypic cell-cell adhesion : ISO:RGD
  • learning or memory : IDA:RGD
  • modulation of chemical synaptic transmission : IMP:SynGO
  • multicellular organismal response to stress : IDA:RGD
  • negative regulation of cell death : IMP:RGD
  • neuron development : IDA:RGD
  • neuron projection development : ISO:RGD
  • peripheral nervous system axon regeneration : IEP:RGD
  • positive regulation of calcium-mediated signaling : ISO:RGD
  • positive regulation of cardiac muscle cell proliferation : IMP:RGD
  • regulation of exocyst assembly : ISO:RGD
  • regulation of semaphorin-plexin signaling pathway : ISO:RGD
  • regulation of sensory perception of pain : IMP:RGD
  • response to activity : IEP:RGD
  • response to cocaine : IDA:RGD
  • response to drug : IDA:RGD
  • response to inorganic substance : IEP:RGD
  • response to lead ion : IDA:RGD
  • thalamus development : IDA:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.