Neural cell adhesion molecule 1 (P13591)

Uniprot ID P13591
Protein Name Neural cell adhesion molecule 1
Gene Name NCAM1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.233
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.(Microbial infection) Acts as a receptor for rabies virus. .
GO - Molecular function
  • identical protein binding : IPI:IntAct
  • virus receptor activity : IEA:UniProtKB-KW
GO - Biological process
  • axon guidance : TAS:Reactome
  • cell adhesion : NAS:ProtInc
  • commissural neuron axon guidance : ISS:ARUK-UCL
  • interferon-gamma-mediated signaling pathway : TAS:Reactome
  • MAPK cascade : TAS:Reactome
  • regulation of semaphorin-plexin signaling pathway : ISS:ARUK-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.