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P13521

Secretogranin-2 (P13521)

Uniprot ID P13521
Protein Name Secretogranin-2
Gene Name SCG2
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.478
Function Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. .
GO - Molecular function
  • chemoattractant activity : IDA:HGNC-UCL
  • cytokine activity : IDA:HGNC-UCL
GO - Biological process
  • angiogenesis : IDA:HGNC-UCL
  • cellular protein metabolic process : TAS:Reactome
  • endothelial cell migration : TAS:HGNC-UCL
  • eosinophil chemotaxis : IDA:HGNC-UCL
  • induction of positive chemotaxis : IDA:HGNC-UCL
  • inflammatory response : TAS:HGNC-UCL
  • intracellular signal transduction : IDA:HGNC-UCL
  • MAPK cascade : IDA:HGNC-UCL
  • negative regulation of endothelial cell apoptotic process : IDA:BHF-UCL
  • negative regulation of endothelial cell proliferation : TAS:HGNC-UCL
  • negative regulation of extrinsic apoptotic signaling pathway : IDA:BHF-UCL
  • positive chemotaxis : IDA:BHF-UCL
  • positive regulation of endothelial cell proliferation : IDA:HGNC-UCL
  • post-translational protein modification : TAS:Reactome
  • protein secretion : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.