Plasminogen activator inhibitor 2, macrophage (P12388)

Uniprot ID	P12388
Protein Name	Plasminogen activator inhibitor 2, macrophage
Gene Name	Serpinb2
Species	Mus musculus (Mouse)

Signal peptide^(a)	Y	Secretome P^(b)	0.639
Function	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Not required for normal murine development or survival.
GO - Molecular function	serine-type endopeptidase inhibitor activity : IBA:GO_Central
GO - Biological process	negative regulation of apoptotic process : IEA:InterPro wound healing : ISO:MGI

Back

^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}