Properdin (P11680)

Uniprot ID P11680
Protein Name Properdin
Gene Name Cfp
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.677
Function A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3-and C5-convertase enzyme complexes.
GO - Molecular function
GO - Biological process
  • complement activation, alternative pathway : IEA:UniProtKB-KW
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.