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P11047

Laminin subunit gamma-1 (P11047)

Uniprot ID P11047
Protein Name Laminin subunit gamma-1
Gene Name LAMC1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.33
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
GO - Molecular function
  • extracellular matrix structural constituent : IMP:HGNC-UCL
GO - Biological process
  • animal organ morphogenesis : IBA:GO_Central
  • cell adhesion : IDA:HGNC-UCL
  • cell migration : IMP:HGNC-UCL
  • cellular protein metabolic process : TAS:Reactome
  • endoderm development : TAS:ProtInc
  • extracellular matrix disassembly : IMP:HGNC-UCL
  • extracellular matrix organization : TAS:Reactome
  • hemidesmosome assembly : IMP:HGNC-UCL
  • positive regulation of epithelial cell proliferation : TAS:HGNC-UCL
  • post-translational protein modification : TAS:Reactome
  • protein-containing complex assembly : IDA:HGNC-UCL
  • substrate adhesion-dependent cell spreading : IDA:BHF-UCL
  • tissue development : IBA:GO_Central
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.