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P10301

Ras-related protein R-Ras (P10301)

Uniprot ID P10301
Protein Name Ras-related protein R-Ras
Gene Name RRAS
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.923
Function Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267). .
GO - Molecular function
  • GDP binding : IDA:UniProtKB
  • GTP binding : IEA:UniProtKB-KW
  • GTPase activity : IDA:UniProtKB
  • protein-containing complex binding : IDA:MGI
GO - Biological process
  • face morphogenesis : IMP:UniProtKB
  • leukocyte differentiation : IMP:UniProtKB
  • negative regulation of cell migration : IEA:Ensembl
  • positive regulation of angiogenesis : IMP:UniProtKB
  • Ras protein signal transduction : TAS:ProtInc
  • regulation of ERK1 and ERK2 cascade : IMP:UniProtKB
  • regulation of protein kinase B signaling : IMP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.