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P0CC10

Leucine-rich repeat-containing protein 4B (P0CC10)

Uniprot ID P0CC10
Protein Name Leucine-rich repeat-containing protein 4B
Gene Name Lrrc4b
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. .
GO - Molecular function
  • signaling receptor binding : ISO:RGD
GO - Biological process
  • positive regulation of synapse assembly : ISO:RGD
  • regulation of postsynaptic density assembly : IDA:SynGO
  • regulation of presynapse assembly : IDA:SynGO
  • synaptic membrane adhesion : IDA:SynGO
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.