| Signal peptide(a) |
Y |
Secretome P(b) |
0.86 |
| Function |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| GO - Molecular function |
- cytokine activity : IDA:BHF-UCL
- enzyme binding : IPI:UniProtKB
- granulocyte colony-stimulating factor receptor binding : IBA:GO_Central
- growth factor activity : IBA:GO_Central
|
| GO - Biological process |
- cellular response to cytokine stimulus : IDA:BHF-UCL
- cellular response to lipopolysaccharide : IEA:Ensembl
- cytokine-mediated signaling pathway : TAS:Reactome
- granulocyte differentiation : NAS:UniProtKB
- immune response : IEA:InterPro
- macrophage differentiation : IBA:GO_Central
- multicellular organism development : TAS:ProtInc
- myeloid cell development : IBA:GO_Central
- negative regulation of neuron death : IEA:Ensembl
- neutrophil differentiation : IBA:GO_Central
- positive regulation of actin cytoskeleton reorganization : IDA:BHF-UCL
- positive regulation of actin filament polymerization : IDA:BHF-UCL
- positive regulation of cell proliferation : IBA:GO_Central
- positive regulation of DNA binding transcription factor activity : IDA:BHF-UCL
- positive regulation of myeloid cell differentiation : IBA:GO_Central
- positive regulation of peptidyl-serine phosphorylation : IDA:BHF-UCL
- positive regulation of peptidyl-tyrosine phosphorylation : IDA:BHF-UCL
- positive regulation of phosphatidylinositol 3-kinase signaling : IDA:BHF-UCL
- positive regulation of protein binding : IDA:BHF-UCL
- positive regulation of protein kinase B signaling : IDA:BHF-UCL
- positive regulation of transcription by RNA polymerase II : IDA:BHF-UCL
- response to ethanol : IEA:Ensembl
|