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P08905

Lysozyme C-2 (P08905)

Uniprot ID P08905
Protein Name Lysozyme C-2
Gene Name Lyz2
Species Mus musculus (Mouse)
Basic Information Experiments (5) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.931
Function Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz2 is active against a range of Gram-positive and Gram-negative bacteria. More effective than Lyz1 in killing Gram-negative bacteria. Lyz1 and Lyz2 are equally effective in killing Gram-positive bacteria. .
GO - Molecular function
  • hydrolase activity, acting on glycosyl bonds : ISO:MGI
  • identical protein binding : ISO:MGI
  • lysozyme activity : IDA:UniProtKB
GO - Biological process
  • cell wall macromolecule catabolic process : IBA:GO_Central
  • cytolysis : IEA:UniProtKB-KW
  • defense response to bacterium : IMP:UniProtKB
  • defense response to Gram-negative bacterium : IDA:UniProtKB
  • defense response to Gram-positive bacterium : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.