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P07724

Serum albumin (P07724)

Uniprot ID P07724
Protein Name Serum albumin
Gene Name Alb
Species Mus musculus (Mouse)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.486
Function Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
GO - Molecular function
  • chaperone binding : ISO:MGI
  • DNA binding : ISS:UniProtKB
  • drug binding : ISS:UniProtKB
  • enzyme binding : ISO:MGI
  • fatty acid binding : ISO:MGI
  • identical protein binding : ISO:MGI
  • oxygen binding : IEA:Ensembl
  • pyridoxal phosphate binding : ISS:UniProtKB
  • toxic substance binding : ISS:UniProtKB
  • zinc ion binding : ISO:MGI
GO - Biological process
  • cellular response to starvation : ISS:UniProtKB
  • hemolysis by symbiont of host erythrocytes : ISS:UniProtKB
  • maintenance of mitochondrion location : ISS:UniProtKB
  • negative regulation of apoptotic process : ISS:UniProtKB
  • positive regulation of circadian sleep/wake cycle, non-REM sleep : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.