Serine/threonine-protein kinase OSR1 (O95747)

Uniprot ID O95747
Protein Name Serine/threonine-protein kinase OSR1
Gene Name OXSR1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.595
Function Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton. .
GO - Molecular function
  • ATP binding : IDA:UniProtKB
  • identical protein binding : IPI:IntAct
  • magnesium ion binding : IDA:UniProtKB
  • protein serine/threonine kinase activity : IDA:UniProtKB
GO - Biological process
  • activation of protein kinase activity : IBA:GO_Central
  • cellular hypotonic response : IEA:Ensembl
  • intracellular signal transduction : IDA:UniProtKB
  • negative regulation of potassium ion transmembrane transporter activity : IEA:Ensembl
  • peptidyl-threonine phosphorylation : IDA:ParkinsonsUK-UCL
  • protein phosphorylation : IDA:UniProtKB
  • regulation of apoptotic process : IBA:GO_Central
  • regulation of mitotic cell cycle : IBA:GO_Central
  • response to oxidative stress : TAS:ProtInc
  • signal transduction by protein phosphorylation : IBA:GO_Central
  • stress-activated protein kinase signaling cascade : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.