| Signal peptide(a) |
N |
Secretome P(b) |
0.394 |
| Function |
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. . |
| GO - Molecular function |
- chaperone binding : IEA:InterPro
- RNA binding : HDA:UniProtKB
- ubiquitin protein ligase binding : IPI:ParkinsonsUK-UCL
|
| GO - Biological process |
- cellular response to epidermal growth factor stimulus : IEA:Ensembl
- cellular response to tumor necrosis factor : IDA:UniProtKB
- negative regulation of apoptotic process : TAS:ProtInc
- negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity : IEA:Ensembl
- negative regulation of protein targeting to mitochondrion : IMP:ParkinsonsUK-UCL
- positive regulation of actin filament polymerization : IEA:Ensembl
- positive regulation of cell adhesion : IEA:Ensembl
- positive regulation of fibroblast migration : IEA:Ensembl
- positive regulation of peptidyl-serine phosphorylation : IEA:Ensembl
- positive regulation of protein kinase B signaling : IEA:Ensembl
- positive regulation of stress fiber assembly : IEA:Ensembl
- protein folding : TAS:ProtInc
- protein localization to plasma membrane : IEA:Ensembl
- regulation of cellular response to heat : TAS:Reactome
- ruffle assembly : IEA:Ensembl
- tumor necrosis factor-mediated signaling pathway : TAS:Reactome
|