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O76076

WNT1-inducible-signaling pathway protein 2 (O76076)

Uniprot ID O76076
Protein Name WNT1-inducible-signaling pathway protein 2
Gene Name WISP2
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.535
Function May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
GO - Molecular function
  • heparin binding : IBA:GO_Central
  • insulin-like growth factor binding : IEA:InterPro
  • integrin binding : IBA:GO_Central
GO - Biological process
  • cell adhesion : IBA:GO_Central
  • cell-cell signaling : TAS:ProtInc
  • negative regulation of cell death : IBA:GO_Central
  • signal transduction : TAS:ProtInc
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.