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O60449

Lymphocyte antigen 75 (O60449)

Uniprot ID O60449
Protein Name Lymphocyte antigen 75
Gene Name LY75
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.454
Function Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes. .
GO - Molecular function
  • carbohydrate binding : IEA:UniProtKB-KW
  • signaling receptor activity : TAS:ProtInc
  • transmembrane signaling receptor activity : IBA:GO_Central
GO - Biological process
  • endocytosis : IEA:UniProtKB-KW
  • immune response : TAS:ProtInc
  • inflammatory response : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.