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O35988

Syndecan-4 (O35988)

Uniprot ID O35988
Protein Name Syndecan-4
Gene Name Sdc4
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.288
Function Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. .
GO - Molecular function
  • fibronectin binding : ISO:MGI
  • identical protein binding : ISO:MGI
  • protein kinase C binding : ISO:MGI
  • thrombospondin receptor activity : ISO:MGI
GO - Biological process
  • inner ear receptor cell stereocilium organization : IGI:MGI
  • negative regulation of T cell proliferation : ISO:MGI
  • neural tube closure : IGI:MGI
  • positive regulation of exosomal secretion : ISO:MGI
  • positive regulation of extracellular exosome assembly : ISO:MGI
  • positive regulation of focal adhesion assembly : ISO:MGI
  • positive regulation of protein kinase activity : ISO:MGI
  • positive regulation of stress fiber assembly : ISO:MGI
  • regulation of fibroblast migration : IMP:UniProtKB
  • ureteric bud development : IEA:Ensembl
  • wound healing : IGI:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.