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O35952

Hydroxyacylglutathione hydrolase, mitochondrial (O35952)

Uniprot ID O35952
Protein Name Hydroxyacylglutathione hydrolase, mitochondrial
Gene Name Hagh
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
GO - Molecular function
  • hydroxyacylglutathione hydrolase activity : IDA:RGD
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • carbohydrate metabolic process : IDA:RGD
  • glutathione biosynthetic process : ISO:RGD
  • glutathione metabolic process : IDA:RGD
  • methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione : IEA:InterPro
  • spermatogenesis : NAS:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.