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O35331

Pyridoxal kinase (O35331)

Uniprot ID O35331
Protein Name Pyridoxal kinase
Gene Name Pdxk
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Required for synthesis of pyridoxal-5-phosphate from vitamin B6. .
GO - Molecular function
  • ATP binding : ISO:RGD
  • drug binding : IDA:RGD
  • lithium ion binding : ISO:RGD
  • magnesium ion binding : ISO:RGD
  • potassium ion binding : ISO:RGD
  • protein homodimerization activity : ISO:RGD
  • pyridoxal binding : IDA:RGD
  • pyridoxal kinase activity : IDA:RGD
  • pyridoxal phosphate binding : ISO:RGD
  • sodium ion binding : ISO:RGD
  • zinc ion binding : ISO:RGD
GO - Biological process
  • cell population proliferation : ISO:RGD
  • negative regulation of apoptotic process : IMP:RGD
  • pyridoxal 5'-phosphate salvage : IBA:GO_Central
  • pyridoxal phosphate biosynthetic process : IDA:RGD
  • response to amine : IEP:RGD
  • response to drug : IEP:RGD
  • response to food : IEP:RGD
  • response to insecticide : IEP:RGD
  • response to progesterone : IEP:RGD
  • response to toxic substance : IEP:RGD
  • response to X-ray : IEP:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.