Extracellular superoxide dismutase [Cu-Zn] (O09164)

Uniprot ID O09164
Protein Name Extracellular superoxide dismutase [Cu-Zn]
Gene Name Sod3
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.447
Function Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. .
GO - Molecular function
  • copper ion binding : IBA:GO_Central
  • superoxide dismutase activity : IDA:MGI
  • zinc ion binding : IBA:GO_Central
GO - Biological process
  • response to copper ion : ISO:MGI
  • response to hypoxia : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.