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O00244

Copper transport protein ATOX1 (O00244)

Uniprot ID O00244
Protein Name Copper transport protein ATOX1
Gene Name ATOX1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.299
Function Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
GO - Molecular function
  • ATPase binding : IEA:Ensembl
  • copper chaperone activity : IDA:UniProtKB
  • copper ion binding : IDA:UniProtKB
  • copper-dependent protein binding : IPI:UniProtKB
  • metallochaperone activity : TAS:UniProtKB
GO - Biological process
  • cellular copper ion homeostasis : IBA:GO_Central
  • copper ion export : IEA:Ensembl
  • copper ion transport : TAS:UniProtKB
  • negative regulation of apoptotic process : IEA:Ensembl
  • response to oxidative stress : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.