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D3ZQP6

Sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (Semaphorin) 7A (Predicted) (D3ZQP6)

Uniprot ID D3ZQP6
Protein Name Sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (Semaphorin) 7A (Predicted)
Gene Name Sema7a
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function
GO - Molecular function
  • chemorepellent activity : IBA:GO_Central
  • integrin binding : ISO:RGD
  • semaphorin receptor binding : IBA:GO_Central
GO - Biological process
  • axon extension : ISO:RGD
  • integrin-mediated signaling pathway : ISO:RGD
  • negative chemotaxis : IBA:GO_Central
  • negative regulation of axon extension involved in axon guidance : IBA:GO_Central
  • neural crest cell migration : IBA:GO_Central
  • neuron projection development : ISO:RGD
  • olfactory lobe development : ISO:RGD
  • positive regulation of axon extension : ISO:RGD
  • positive regulation of cell migration : IBA:GO_Central
  • positive regulation of ERK1 and ERK2 cascade : ISO:RGD
  • positive regulation of macrophage cytokine production : ISO:RGD
  • positive regulation of protein phosphorylation : ISO:RGD
  • regulation of inflammatory response : ISO:RGD
  • semaphorin-plexin signaling pathway : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.