Glutathione S-transferase pi (B6DYQ7)

Uniprot ID B6DYQ7
Protein Name Glutathione S-transferase pi
Gene Name Gstp1
Species Rattus norvegicus (Rat)
Signal peptide(a) N Secretome P(b)
Function
GO - Molecular function
  • dinitrosyl-iron complex binding : IEA:Ensembl
  • fatty acid binding : IEA:Ensembl
  • glutathione peroxidase activity : IEA:Ensembl
  • glutathione transferase activity : IEA:Ensembl
  • S-nitrosoglutathione binding : IEA:Ensembl
GO - Biological process
  • glutathione metabolic process : IEA:Ensembl
  • linoleic acid metabolic process : IEA:Ensembl
  • negative regulation of ERK1 and ERK2 cascade : IEA:Ensembl
  • negative regulation of extrinsic apoptotic signaling pathway : IEA:Ensembl
  • negative regulation of interleukin-1 beta production : IEA:Ensembl
  • negative regulation of JUN kinase activity : IEA:Ensembl
  • negative regulation of monocyte chemotactic protein-1 production : IEA:Ensembl
  • negative regulation of nitric-oxide synthase biosynthetic process : IEA:Ensembl
  • negative regulation of tumor necrosis factor production : IEA:Ensembl
  • xenobiotic metabolic process : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.