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B0BNM1

NAD(P)H-hydrate epimerase (B0BNM1)

Uniprot ID B0BNM1
Protein Name NAD(P)H-hydrate epimerase
Gene Name Naxe
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Catalyzes the epimerization of the S-and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. .
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
  • NADHX epimerase activity : IDA:MGI
  • NADPHX epimerase activity : IDA:MGI
  • nucleotide binding : IEA:UniProtKB-KW
  • protein homodimerization activity : ISO:RGD
GO - Biological process
  • nicotinamide nucleotide metabolic process : ISO:RGD
  • protein homotetramerization : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.