Signal peptide(a) |
N |
Secretome P(b) |
0.0 |
Function |
Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay. . |
GO - Molecular function |
- chromatin binding : IDA:MGI
- DNA binding : IEA:UniProtKB-KW
- lipid binding : IDA:MGI
- mRNA 3'-UTR binding : IDA:MGI
- mRNA binding : IDA:MGI
- ribonucleoprotein complex binding : IDA:MGI
- translation regulator activity : IDA:MGI
|
GO - Biological process |
- mRNA stabilization : IMP:MGI
- negative regulation of binding : IMP:MGI
- negative regulation of translation : IDA:MGI
- oogenesis : IMP:MGI
- regulation of transcription, DNA-templated : IEA:InterPro
- spermatid development : IMP:MGI
|