N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (Q9Z222)

Uniprot ID Q9Z222
Protein Name N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
Gene Name B3GNT2
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.605
Function Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains (PubMed:9892646). Probably constitutes the main polylactosamine synthase (PubMed:17890318). .
GO - Molecular function
  • galactosyltransferase activity : IEA:InterPro
  • N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity : ISS:UniProtKB
GO - Biological process
  • axon guidance : IMP:MGI
  • cellular response to leukemia inhibitory factor : IEP:MGI
  • poly-N-acetyllactosamine biosynthetic process : ISS:UniProtKB
  • protein glycosylation : IMP:MGI
  • sensory perception of smell : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.