Potassium-transporting ATPase alpha chain 2 (Q9Z1W8)

Uniprot ID Q9Z1W8
Protein Name Potassium-transporting ATPase alpha chain 2
Gene Name Atp12a
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.394
Function Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • metal ion binding : IEA:UniProtKB-KW
  • potassium : IEA:UniProtKB-EC
  • sodium : IEA:InterPro
GO - Biological process
  • metal ion transport : ISO:MGI
  • potassium ion homeostasis : IMP:MGI
  • regulation of pH : IMP:MGI
  • response to metal ion : ISO:MGI
  • response to organic cyclic compound : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.