| Signal peptide(a) |
N |
Secretome P(b) |
0.0 |
| Function |
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. |
| GO - Molecular function |
- extracellular matrix constituent conferring elasticity : IBA:GO_Central
- identical protein binding : IPI:IntAct
- integrin binding involved in cell-matrix adhesion : IMP:CAFA
|
| GO - Biological process |
- aortic valve morphogenesis : ISS:BHF-UCL
- cell adhesion : TAS:ProtInc
- cell migration : IMP:CAFA
- cell-matrix adhesion : IMP:CAFA
- elastic fiber assembly : ISS:BHF-UCL
- negative regulation of angiogenesis : ISS:BHF-UCL
- negative regulation of cell activation : ISS:BHF-UCL
- negative regulation of collagen biosynthetic process : ISS:BHF-UCL
- negative regulation of collagen fibril organization : ISS:BHF-UCL
- negative regulation of ERK1 and ERK2 cascade : ISS:BHF-UCL
- negative regulation of gene expression : ISS:BHF-UCL
- negative regulation of macrophage migration : ISS:BHF-UCL
- negative regulation of pathway-restricted SMAD protein phosphorylation : ISS:BHF-UCL
- negative regulation of transforming growth factor beta receptor signaling pathway : ISS:BHF-UCL
- negative regulation of vascular endothelial growth factor receptor signaling pathway : ISS:BHF-UCL
- positive regulation of cell-substrate adhesion : IEA:Ensembl
- positive regulation of extracellular matrix assembly : ISS:BHF-UCL
- positive regulation of gene expression : ISS:BHF-UCL
|