Actin-related protein 2/3 complex subunit 1B (Q9WV32)

Uniprot ID Q9WV32
Protein Name Actin-related protein 2/3 complex subunit 1B
Gene Name Arpc1b
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.321
Function Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. .
GO - Molecular function
  • actin filament binding : IBA:GO_Central
  • protein-containing complex binding : ISO:MGI
  • structural constituent of cytoskeleton : ISO:MGI
GO - Biological process
  • Arp2/3 complex-mediated actin nucleation : ISO:MGI
  • response to estradiol : IEA:Ensembl
  • response to estrogen : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.