Protocadherin alpha-4 (Q9UN74)

Uniprot ID Q9UN74
Protein Name Protocadherin alpha-4
Gene Name PCDHA4
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.127
Function Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain. .
GO - Molecular function
  • calcium ion binding : ISS:UniProtKB
  • identical protein binding : ISS:UniProtKB
GO - Biological process
  • cell adhesion : IBA:GO_Central
  • homophilic cell adhesion via plasma membrane adhesion molecules : IEA:InterPro
  • nervous system development : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.