Protein S100-A6 (Q9R2B7)

Uniprot ID Q9R2B7
Protein Name Protein S100-A6
Gene Name S100a6
Species Rattus norvegicus (Rat)
Signal peptide(a) N Secretome P(b)
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity). .
GO - Molecular function
  • calcium ion binding : IDA:RGD
  • calcium-dependent protein binding : ISO:RGD
  • ion transmembrane transporter activity : IDA:RGD
  • protein homodimerization activity : ISO:RGD
  • S100 protein binding : ISO:RGD
  • tropomyosin binding : ISO:RGD
  • zinc ion binding : ISO:RGD
GO - Biological process
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.