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Q9R1Z7

6-pyruvoyl tetrahydrobiopterin synthase (Q9R1Z7)

Uniprot ID Q9R1Z7
Protein Name 6-pyruvoyl tetrahydrobiopterin synthase
Gene Name Pts
Species Mus musculus (Mouse)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
GO - Molecular function
  • 6-pyruvoyltetrahydropterin synthase activity : IDA:MGI
  • identical protein binding : IPI:MGI
  • metal ion binding : IEA:UniProtKB-KW
  • protein homodimerization activity : IPI:MGI
GO - Biological process
  • tetrahydrobiopterin biosynthetic process : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.