Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
Q9R190

Metastasis-associated protein MTA2 (Q9R190)

Uniprot ID Q9R190
Protein Name Metastasis-associated protein MTA2
Gene Name Mta2
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (1) Interactions
Signal peptide(a) N Secretome P(b) 0.589
Function May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
GO - Molecular function
  • chromatin binding : IEA:InterPro
  • DNA binding transcription factor activity : IEA:InterPro
  • histone deacetylase activity : IDA:MGI
  • histone deacetylase binding : ISO:MGI
  • RNA polymerase II repressing transcription factor binding : ISO:MGI
  • RNA polymerase II transcription factor binding : ISO:MGI
  • transcription factor activity, transcription factor binding : IDA:UniProtKB
  • transcription regulatory region DNA binding : IDA:UniProtKB
  • transcription regulatory region sequence-specific DNA binding : IEA:Ensembl
  • zinc ion binding : IEA:InterPro
GO - Biological process
  • chromatin remodeling : TAS:MGI
  • DNA methylation : IMP:MGI
  • DNA packaging : TAS:MGI
  • negative regulation of transcription by RNA polymerase II : IDA:MGI
  • negative regulation of transcription, DNA-templated : IDA:UniProtKB
  • positive regulation of transcription by RNA polymerase II : IDA:MGI
  • regulation of fibroblast migration : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.