Signal peptide(a) |
N |
Secretome P(b) |
0.629 |
Function |
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. . |
GO - Molecular function |
- alpha-2A adrenergic receptor binding : ISO:MGI
- cysteine-type endopeptidase activity : ISS:UniProtKB
- ligase activity : IEA:UniProtKB-KW
- omega peptidase activity : ISS:UniProtKB
- thiol-dependent ubiquitin-specific protease activity : IDA:MGI
- ubiquitin binding : IDA:MGI
- ubiquitin protein ligase binding : ISO:MGI
|
GO - Biological process |
- adult walking behavior : IMP:MGI
- axon target recognition : IMP:MGI
- axonal transport of mitochondrion : IMP:MGI
- axonogenesis : IMP:MGI
- cell proliferation : IMP:MGI
- eating behavior : IGI:MGI
- muscle fiber development : IGI:MGI
- negative regulation of MAP kinase activity : ISO:MGI
- neuromuscular process : IMP:MGI
- protein deubiquitination : ISS:UniProtKB
- response to ischemia : IMP:MGI
- sensory perception of pain : ISO:MGI
- ubiquitin-dependent protein catabolic process : ISO:MGI
|