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Q9QXS1

Plectin (Q9QXS1)

Uniprot ID Q9QXS1
Protein Name Plectin
Gene Name Plec
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.0
Function Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • ankyrin binding : ISO:MGI
  • cadherin binding : ISO:MGI
  • cytoskeletal protein binding : ISO:MGI
  • protein N-terminus binding : ISO:MGI
  • structural constituent of cytoskeleton : ISO:MGI
  • structural constituent of muscle : ISO:MGI
GO - Biological process
  • hemidesmosome assembly : ISS:UniProtKB
  • response to nutrient : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.