Signal peptide(a) |
N |
Secretome P(b) |
|
Function |
Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity). Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. . |
GO - Molecular function |
- sequence-specific DNA binding : IDA:RGD
- sequence-specific DNA binding : ISO:MGI
|
GO - Biological process |
- catecholamine metabolic process : IEP:RGD
- cellular response to mechanical stimulus : IEP:RGD
- cerebellar granule cell differentiation : IEP:RGD
- neuron differentiation : NAS:UniProtKB
- positive regulation of cardiac muscle hypertrophy : IMP:UniProtKB
- positive regulation of cell growth : IDA:UniProtKB
- positive regulation of macromolecule biosynthetic process : IDA:UniProtKB
- positive regulation of NF-kappaB transcription factor activity : IDA:UniProtKB
- positive regulation of protein metabolic process : IDA:UniProtKB
- regulation of barbed-end actin filament capping : ISS:UniProtKB
- regulation of cell size : ISO:RGD
- skeletal muscle tissue regeneration : IEP:RGD
- striated muscle cell differentiation : IEP:RGD
- catecholamine metabolic process : IEA:Ensembl
- cellular response to mechanical stimulus : IEA:Ensembl
- cerebellar granule cell differentiation : IEA:Ensembl
- positive regulation of cardiac muscle hypertrophy : ISS:UniProtKB
- positive regulation of cell growth : ISS:UniProtKB
- positive regulation of macromolecule biosynthetic process : ISS:UniProtKB
- positive regulation of NF-kappaB transcription factor activity : ISS:UniProtKB
- positive regulation of protein metabolic process : ISS:UniProtKB
- regulation of barbed-end actin filament capping : ISS:UniProtKB
- regulation of cell size : ISO:MGI
- skeletal muscle tissue regeneration : IEA:Ensembl
- striated muscle cell differentiation : IEA:Ensembl
|