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Q9DCD0

6-phosphogluconate dehydrogenase, decarboxylating (Q9DCD0)

Uniprot ID Q9DCD0
Protein Name 6-phosphogluconate dehydrogenase, decarboxylating
Gene Name Pgd
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.623
Function Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. .
GO - Molecular function
  • carbohydrate binding : ISO:MGI
  • carboxylic acid binding : ISO:MGI
  • NADP binding : ISO:MGI
  • phosphogluconate dehydrogenase (decarboxylating) activity : IDA:MGI
GO - Biological process
  • carbohydrate metabolic process : ISO:MGI
  • D-gluconate metabolic process : ISO:MGI
  • NADP metabolic process : ISO:MGI
  • oxidation-reduction process : ISO:MGI
  • pentose biosynthetic process : IDA:MGI
  • pentose-phosphate shunt : ISS:UniProtKB
  • pentose-phosphate shunt, oxidative branch : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.