AMP deaminase 2 (Q9DBT5)

Uniprot ID Q9DBT5
Protein Name AMP deaminase 2
Gene Name Ampd2
Species Mus musculus (Mouse)
Signal peptide(a) N Secretome P(b) 0.593
Function AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle (By similarity). .
GO - Molecular function
  • AMP deaminase activity : IMP:CACAO
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • AMP metabolic process : IMP:CACAO
  • ATP metabolic process : IMP:CACAO
  • cholesterol homeostasis : IMP:MGI
  • cyclic purine nucleotide metabolic process : ISS:UniProtKB
  • energy homeostasis : IMP:MGI
  • glomerular visceral epithelial cell development : IMP:MGI
  • GTP metabolic process : IMP:CACAO
  • IMP biosynthetic process : IMP:MGI
  • IMP salvage : IEA:UniProtKB-UniPathway
  • nucleotide metabolic process : IMP:MGI
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.