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Q9DBH5

Vesicular integral-membrane protein VIP36 (Q9DBH5)

Uniprot ID Q9DBH5
Protein Name Vesicular integral-membrane protein VIP36
Gene Name Lman2
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.273
Function Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity). .
GO - Molecular function
  • carbohydrate binding : ISO:MGI
  • heat shock protein binding : ISO:MGI
  • mannose binding : ISO:MGI
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • positive regulation of phagocytosis : IMP:UniProtKB
  • protein transport : IEA:UniProtKB-KW
  • retrograde vesicle-mediated transport, Golgi to ER : ISO:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.